Toy Medical Co., Ltd. (Headquarters: Minami-ku, Kumamoto City, Kumamoto Prefecture; President: Hidenori Takeshita) has revealed, in joint research with Kumamoto University, a national university corporation, that ammonium alginate, a type of dietary fiber derived from seaweed, has the effect of suppressing kidney inflammation and fibrosis that worsen due to excessive salt intake, in a unilateral renal ureteral ligation model mouse, which is one of the chronic kidney disease (CKD) models.

The results of this research were published in the international academic journal "Results in Chemistry" on April 24, 2026.

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[Announcement] Joint Research with Kumamoto University Demonstrates Ammonium Alginate Suppresses Renal Inflammation and Fibrosis Caused by Excessive Salt Intake—Findings Published in International Scientific Journal “Results in Chemistry”

Toy Medical Co., Ltd. (Headquarters: Minami-ku, Kumamoto City, Kumamoto Prefecture; President & CEO: Hidenori Takeshita), in a joint research project with Kumamoto University, has demonstrated that ammonium alginate—a type of seaweed-derived dietary fiber—effectively suppresses renal inflammation and fibrosis exacerbated by excessive salt intake. This breakthrough was confirmed using a unilateral ureteral obstruction mouse model, which is a recognized model for chronic kidney disease (CKD).

The research findings were successfully published in the international scientific journal “Results in Chemistry” on April 24, 2026.

Toy Medical will continue to advance its research into the efficacy and potential of alginates. Through our proprietary “salt offset technology,” we remain committed to realizing a world where people never have to compromise on either delicious food or good health.

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